Intra-articular infiltration under fluoroscopy involves injecting an anti-inflammatory agent into the joints, bursa or tendons to relieve pain and inflammation. Facet blocks under fluoroscopy involve injecting the drug (cortisone) into the facet joints of the spine (cervical, dorsal or lumbar) to temporarily relieve pain.

Several injections may be required. If so, a time interval is recommended between each injection (maximum of three injections per year at the same site). Selective epidurals, commonly called "foraminal blocks", involve injecting cortisone where the nerve roots of the spine emerge.